The Centauri System is CE-marked and available in select EU countries.
It is not commercially available in the United States.
CardioFocus is the exclusive distributor of the Centauri System.
Overview
The CardioFocus Centauri™ PFA System is a cutting edge, open platform design that supports your current focal contact force catheter workflow, leveraging a custom monopolar waveform designed to achieve transmural lesions while eliminating microbubbles and muscle stimulation. Seamlessly integrating into your existing workflows, the Centauri System enables physicians to confidently deliver durable PFA lesions while enhancing procedural efficiency, safety, and patient outcomes.
System features include:
Three selectable monopolar PFA doses offered at 19, 22, and 25 Amps for lesion control
Impedance balanced energy delivery to ensure consistent, predictable transmural lesions
Current control algorithm ensures consistent energy output in all patients
Versatility through an open platform supporting three commercially available contact force catheters:
TactiCath Sensor Enabled™
THERMOCOOL SMARTTOUCH™
INTELLANAV STABLEPOINT™
Compatible Mapping Systems &
Ablation Catheters
Custom monopolar waveform
The Centauri System utilizes the custom WAVE1 monopolar biphasic waveform to deliver transmural PFA lesions while effectively eliminating the potential for microbubbles and muscle stimulation.
Simulation of a 19A monopolar dose, data on file
In a monopolar configuration, an electric field is created at the catheter tip that is directed towards a remote dispersive electrode. As a result, monopolar devices achieve deeper lesions than equivalent bipolar configurations.
The six-pillar approach to PEF therapy
The six-pillar approach to PEF therapy for use in conventional intracardiac ablation procedures gives electrophysiologists a next generation ablation tool designed for the highest level of safety and efficacy.
Wave 1
The proprietary waveform CardioFocus has customized for use in conventional intracardiac ablation procedures balances full-thickness tissue ablation while limiting the effects on extracardiac structures.
Energy setting
The Centauri Constellation energy delivery scheme gives physicians control, allowing one of three doses to be used for varying tissue thickness.
Zero bubbles
The WAVE1 waveform was designed to significantly reduce microbubbles which may embolize to the brain. Centauri has been designed using WAVE1 energy for safe and effective delivery of PEF. Our goal is a safe and effective delivery of PEF with zero bubbles.
Monopolar
Centauri uses monopolar PEF delivery for lesion control.
Automatic impedance
Tissue impedance is patient specific and impacts lesion formation during PEF delivery. Centauri monitors this between every delivery and optimizes dosing parameters to ensure consistent predictable transmural lesions.
Current control
The Centauri current control algorithm ensures a consistent current output from the catheter in all patients ensuring predictable lesion size.
Clinical studies
Safety outcomes
Esophageal injuries
0%
Phrenic nerve injuries
0%
PV stenosis
0%
Incidence of microbubbles per avaluation on intracardiac echocardiagram during ablation
0%
Efficacy outcomes
Overall, 89% PV isolation at 3 months using Centauri System with three compatible commercially available cardiac ablation catheters
Eclipse-AF PV isolation rate at 3 months
Overall PV Isolation Durablity = 89%
92% PV isolation at 3 months using the Centauri System with the Biosense Webster Thermocool Smarttouch™ ablation catheter
90% PV isolation at 3 months using the Centauri System with the Boston Scientific Intellanav Stablepoint™ ablation catheter
84% PV isolation at 3 months using the Centauri System with the Abbott TactiCath™ Contact Force Sensing Catheter, Sensor Enabled™
Anić A et al. Pulsed field ablation using focal contact force-sensing catheters for treatment of atrial fibrillation: acute and 90-day invasive remapping results. Europace. 2023 Jun 2;25(6):euad147.

Centauri Live Case
Watch Dr. Anic at KBC Split in Croatia perform a focal PFA ablation using the Centauri System.
Centauri Live Case
Watch Dr. Atul Verma at Southlake Regional Health Centre in Newmarket, Ontario perform a focal PFA ablation using the Centauri System.
PFA: Bipolar vs Monopolar Energy Delivery
Learn the clinical benefits and limitations of bipolar and monopolar energy deliver with pulsed field ablation